Seminare über Quantenfeldtheorie

Evolutionary adaptations arise from an intricate interplay of deterministic selective forces and random reproductive or mutational events, and the relative roles of these two types of influences is the subject of a long-standing controversy. In general, the predictability of adaptive trajectories is governed by the genetic constraints imposed by the structure of the underlying fitness landscape as well as by the supply rate of beneficial mutations, the latter being determined primarily by the population size. Here recent results pertaining to two aspects of the problem will be reported. First, we address the statistics of fitness-monotonic ("selectively accessible") mutational pathways in random models of fitness landscapes and point out the analogy to percolation problems. Second, we use large-scale simulations on an empirically determined fitness landscape to show that, contrary to common wisdom, the predictability of adaptive trajectories varies non-monotonically with population size.

Kontakt: K.-H. Rehren

Kontakt: K.-H. Rehren

Kontakt: K.-H. Rehren

Kontakt: K.-H. Rehren

Kontakt: K.-H. Rehren

Kontakt: K.-H. Rehren